THE NEUTRALIZATION OF ANTIPNEUMOCOCCUS IMMUNE BODIES BY INFECTED EXUDATES AND SERA
نویسندگان
چکیده
منابع مشابه
The Distribution of the Immune Bodies Occurring in Antipneumococcus Serum
The immune bodies of antipneumococcus serum are completely precipitated by 38 to 42 per cent. saturation with ammonium sulphate. They are incompletely precipitated by (a) ammonium sulphate in less than 38 per cent. saturation, (b) saturation with sodium chloride, (c) dilution and saturation with carbon dioxide, (d) removal of crystalloids by dialysis. The immune bodies of antipneumococcus serum...
متن کاملSpecific Proteins of Antipneumococcus Sera Ii. Immunological Fractionation 01~ Type I Antipneumococcus Horse and Rabbit Sera
In the preceding paper of this series (1) it was reported that the amount of specific antibody precipitable by the capsular polysaccharide is related to the mouse protective value of Type I antipneumococcus serum only under certain well defined conditions. Thus with Type I antipneumococcus rabbit serum there was a direct proportionality between the two determined values. The protective ratio fo...
متن کاملThe Precipitin Reaction of Antipneumococcus Sera
The precipitin indices for a number of monovalent and polyvalent antipneumococcus sera were determined under known conditions, and found to vary as did the number of protective units. The ratio precipitin index/protective units in monovalent sera was found to lie between 2.8 and 4.8 for Type I and to be about ten times greater for Type III. Lower values were found in polyvalent horses and when ...
متن کاملProperties of the Type Specific Proteins of Antipneumococcus Sera
The generally held view has been that in any immune serum only a single antibody would be induced by and react with a single antigen. Were this true the various manifestations of antibody activity should show a quantitative parallelism. It has already been shown (1), however, that with antipneumococcus horse serum the mouse protective potency does not parallel the maximum amount of specifically...
متن کاملA Note on the Production of Antipneumococcus Sera
Horses immunized to Type I pneumococci developed serum, 0.1 cc. of which protected against 0.5 cc. of a virulent culture, 0.000001 cc. of which killed mice in less than 40 hours. Protective tests of serum from horses immunized to Type II organisms varied, 0.1 cc. protecting, however, in certain instances against 0.1 and 0.01 cc. of virulent homologous culture. Types I and II sera obtained in ou...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1917
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.26.4.453